Ilana's PNAS paper that shows that two ABC transporters that transport the same molecules operate by very different
We are interested in how molecular mechanisms adapt to serve their specific physiological roles.
mechanisms. These different mechanisms allow the bacteria to adapt to different extracellular concentrations of the transported molecule.
We use molecular simulations to visualize the movements of proteins.
Jessica's movie, generated using a novel hybrid approach of molecular simulations, shows the opening and closing of the ATP binding sites in the Maltose ABC transporter MalFGK (made in collaboration with Burcu Aykaç Fas and Burçin Acar the lab of Turkan Haliloglu).